Considerations To Know About Conolidine alkaloid for chronic pain
Most not long ago, it has been identified that conolidine and the above derivatives act over the atypical chemokine receptor 3 (ACKR3. Expressed in equivalent spots as classical opioid receptors, it binds to some big range of endogenous opioids. Unlike most opioid receptors, this receptor acts to be a scavenger and does not activate a 2nd messenger